Description

2-Iodophenyl Trifluoromethanesulfonate is a versatile and highly reactive aryl triflate derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as an excellent electrophile in cross-coupling reactions, enabling the efficient construction of complex biaryl and heteroaryl structures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop active pharmaceutical ingredients (APIs), functional materials, and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura, Stille, and Negishi cross-coupling reactions for synthesizing novel drug candidates and APIs.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides by introducing the iodophenyl moiety into complex molecules.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized phosphine or N-heterocyclic carbene (NHC) ligands.
• Materials Science: Building block for organic electronic materials, such as OLEDs and semiconductors, where the iodine atom allows for further functionalization.
• Chemical Research: Employed in palladium-catalyzed C-H activation and carbon-heteroatom bond formation studies.
• Radiopharmaceuticals: Potential precursor for iodine-123 or iodine-131 labeled compounds used in medical imaging and therapy.

Basic Information

Product Name	2-Iodophenyl Trifluoromethanesulfonate
CAS No.	129112-26-1
Molecular Formula	C7H4F3IO3S
Molecular Weight	375.07 g/mol
Synonyms	2-Iodophenyl Triflate; o-Iodophenyl Trifluoromethanesulfonate; (2-Iodophenyl) Triflate; Trifluoromethanesulfonic Acid 2-Iodophenyl Ester; 1-Iodo-2-(trifluoromethanesulfonyloxy)benzene; 2-Iodo-1-(trifluoromethanesulfonyloxy)benzene; 2-Iodophenyl Trifluoromethylsulfonate
EINECS	Contact for details

Quality Control

Our 2-Iodophenyl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.