Description

1H-1,2,3-Triazole-4-Carboxaldehyde, 1-(1,1-Dimethylethyl)- (9Ci) is a high-value, functionalized triazole derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a reactive aldehyde group and a sterically hindered tert-butyl-protected triazole ring, makes it indispensable for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the triazole scaffold plays a crucial role in binding.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functional polymers, metal-organic frameworks (MOFs), and other advanced materials where its aldehyde group enables further functionalization.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes due to the bio-orthogonal reactivity potential of the triazole ring.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	1H-1,2,3-Triazole-4-Carboxaldehyde, 1-(1,1-Dimethylethyl)- (9Ci)
CAS No.	129027-65-2
Molecular Formula	C7H11N3O
Molecular Weight	153.18 g/mol
Synonyms	1-tert-Butyl-1H-1,2,3-triazole-4-carbaldehyde; 1-(tert-Butyl)-1H-1,2,3-triazole-4-carboxaldehyde; 4-Formyl-1-tert-butyl-1,2,3-triazole; 1-(1,1-Dimethylethyl)-1H-1,2,3-triazole-4-carboxaldehyde; tert-Butyl-1,2,3-triazole-4-carboxaldehyde; 1-tert-Butyl-4-formyl-1,2,3-triazole
EINECS	Contact for details

Quality Control

Every batch of 1H-1,2,3-Triazole-4-Carboxaldehyde, 1-(1,1-Dimethylethyl)- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as assay purity (by HPLC/NMR), identity confirmation, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, it is recommended to keep the material under an inert atmosphere at temperatures between 2°C and 8°C to maintain stability and purity. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.