Description

1H-Indene-4-Carboxaldehyde, 2,3,3A,4,5,7A-Hexahydro-, [3As-(3Aalpha,4Alpha,7Abeta)]- (9Ci) is a specialized, high-purity chiral aldehyde derivative of the indane class, serving as a critical building block in advanced organic synthesis. Its rigid, fused bicyclic structure and defined stereochemistry make it a valuable precursor for constructing complex molecular architectures with precise spatial orientation. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for synthesizing novel active ingredients, chiral ligands, and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its specific stereochemistry can influence biological activity.
• Chiral Ligand & Catalyst Development: Serves as a foundational structure for creating novel asymmetric catalysts and ligands used in enantioselective synthesis.
• Fine Chemical & Flavor/Fragrance Precursor: Employed in the synthesis of complex fragrance molecules and high-value fine chemicals requiring specific stereochemical purity.
• Material Science Research: Investigated as a monomer or building block for novel polymers and functional organic materials with tailored properties.

Basic Information

Product Name	1H-Indene-4-Carboxaldehyde, 2,3,3A,4,5,7A-Hexahydro-, [3As-(3Aalpha,4Alpha,7Abeta)]- (9Ci)
CAS No.	129026-21-7
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	(3aS,4R,7aR)-2,3,3a,4,5,7a-Hexahydro-1H-indene-4-carboxaldehyde; Hexahydro-1H-indene-4-carboxaldehyde (stereoisomer); 4-Formyl-2,3,3a,4,5,7a-hexahydro-1H-indene; (3aα,4α,7aβ)-Hexahydro-1H-indene-4-carboxaldehyde; Indane-4-carboxaldehyde derivative; Chiral indane aldehyde; Stereoisomer of CAS 129026-21-7.
EINECS	Contact for details

Quality Control

Every batch of our 1H-Indene-4-Carboxaldehyde, 2,3,3A,4,5,7A-Hexahydro-, [3As-(3Aalpha,4Alpha,7Abeta)]- (9Ci) is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, chiral analysis, and NMR to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all critical parameters are provided with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and batch-to-batch consistency for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.