Description

2,6-Difluoro-3,4-Dihydroxyphenylalanine is a fluorinated derivative of the amino acid L-DOPA, representing a specialized building block in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and biochemical probes, particularly those targeting the central nervous system. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, neurochemical research, and the synthesis of complex fluorinated molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel fluorinated drug candidates, especially for neurological and psychiatric disorders.
• Biochemical Research: Used as a tool compound in neuroscience research to study dopamine metabolism and receptor interactions.
• Radiopharmaceutical Development: Serves as a starting material for the synthesis of fluorine-18 labeled tracers for Positron Emission Tomography (PET) imaging.
• Organic Synthesis Building Block: Utilized in the preparation of complex fluorinated organic molecules for material science and agrochemical research.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2,6-Difluoro-3,4-Dihydroxyphenylalanine
CAS No.	128812-04-4
Molecular Formula	C9H9F2NO4
Molecular Weight	233.17 g/mol
Synonyms	2,6-Difluoro-DOPA; 2,6-Difluoro-3,4-dihydroxy-L-phenylalanine; 2,6-DFDOPA; (2S)-2-Amino-3-(2,6-difluoro-3,4-dihydroxyphenyl)propanoic acid; L-2,6-Difluoro-3,4-dihydroxyphenylalanine; 6-Fluoro-α-fluorodopa; 2,6-Difluorodopa; 128812-04-4
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3,4-Dihydroxyphenylalanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its properties of being easily oxidized and hygroscopic. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.