Description

2-Bromo-1-[4-(2-Thienyl)Phenyl]-1-Ethanone is a specialized organic building block featuring a bromoacetyl group linked to a biaryl system containing a thiophene moiety. This compound is valued for its role as a key synthetic intermediate in the development of advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its reactive bromoacetyl group.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of organic semiconductors and conductive polymers.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysis.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and protein interactions due to its electrophilic site.

Basic Information

Product Name	2-Bromo-1-[4-(2-Thienyl)Phenyl]-1-Ethanone
CAS No.	128746-80-5
Molecular Formula	C12H9BrOS
Molecular Weight	281.17 g/mol
Synonyms	2-Bromo-1-(4-(thiophen-2-yl)phenyl)ethan-1-one; 2-Bromo-1-[4-(2-thienyl)phenyl]ethanone; 4-(2-Thienyl)phenacyl bromide; 2-Bromo-4'-(2-thienyl)acetophenone; α-Bromo-4-(2-thienyl)acetophenone; 1-(4-(Thiophen-2-yl)phenyl)-2-bromoethanone
EINECS	Contact for details

Quality Control

Our production of 2-Bromo-1-[4-(2-Thienyl)Phenyl]-1-Ethanone adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic workflows. Each lot is characterized by advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.