Description

(1R,4Ar,6S,8As)-6,8A-Dimethyl-5-Methylidene-1,4,4A,6,7,8-Hexahydronaphthalene-1,2-Dicarbaldehyde is a high-purity, advanced synthetic intermediate characterized by its unique decalin-based dicarbaldehyde structure. This compound matters for its role as a critical chiral building block in the synthesis of complex natural products and active pharmaceutical ingredients (APIs), enabling precise stereochemical control. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of steroidal frameworks, terpenoid derivatives, and other complex bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where its rigid, functionalized structure can impart specific biological activity.
• Fine Chemical Production: Acts as a versatile building block for creating specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial Research: Employed in methodological studies and total synthesis projects to explore new chemical transformations and reaction pathways.
• Material Science Precursor: Potential use in the development of specialized polymers or ligands where its aldehyde groups and defined geometry are advantageous.

Basic Information

Product Name	(1R,4Ar,6S,8As)-6,8A-Dimethyl-5-Methylidene-1,4,4A,6,7,8-Hexahydronaphthalene-1,2-Dicarbaldehyde
CAS No.	128718-14-9
Molecular Formula	C₁₅H₂₀O₂
Molecular Weight	232.32 g/mol
Synonyms	6,8A-Dimethyl-5-methylidene-1,4,4a,6,7,8-hexahydronaphthalene-1,2-dicarbaldehyde; (1R,4aR,6S,8aS)-6,8a-Dimethyl-5-methylidene-1,4,4a,6,7,8-hexahydronaphthalene-1,2-dicarboxaldehyde; Decalin-1,2-dicarbaldehyde derivative; Chiral decalin dialdehyde; CAS 128718-14-9
EINECS	Contact for details

Quality Control

Our (1R,4Ar,6S,8As)-6,8A-Dimethyl-5-Methylidene-1,4,4A,6,7,8-Hexahydronaphthalene-1,2-Dicarbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting R&D and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee reliable and reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage, consider storage under an inert gas such as argon or nitrogen in a sealed container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.