Description

(3S,7R,10R,11R)-10-[(2R,3R,4R,5R,6S)-4-Amino-3,5-Dihydroxy-6-Methyl-Oxan-2-Yl]Oxy-3,11-Diethyl-7-Methyl-1-Azacyclotetradecan-2-One is a complex, stereochemically defined macrolide compound of significant interest in advanced organic synthesis and pharmaceutical research. Its intricate structure, featuring multiple chiral centers and a glycosidic linkage, makes it a valuable chiral building block and intermediate for the development of novel bioactive molecules. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require precise molecular scaffolds for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of novel macrolide antibiotics and other complex therapeutic agents.
• Biochemical Research: Used as a standard or probe in studies investigating enzyme inhibition, receptor binding, and structure-activity relationships (SAR).
• Asymmetric Synthesis: Acts as a sophisticated starting material or template for constructing complex natural products and analogs via stereocontrolled reactions.
• Process Chemistry Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) requiring high stereochemical fidelity.
• Academic Research: Utilized in university and institutional labs for methodological development in total synthesis and glycoscience.
• Reference Standard: Provides a high-purity compound for analytical method development, validation, and quality control in regulatory submissions.

Basic Information

Product Name	(3S,7R,10R,11R)-10-[(2R,3R,4R,5R,6S)-4-Amino-3,5-Dihydroxy-6-Methyl-Oxan-2-Yl]Oxy-3,11-Diethyl-7-Methyl-1-Azacyclotetradecan-2-One
CAS No.	128563-23-5
Molecular Formula	C27H52N2O6
Molecular Weight	500.72 g/mol
Synonyms	10-O-(4-Amino-4,6-dideoxy-α-D-mannopyranosyl)-3,11-diethyl-7-methyl-1-azacyclotetradecan-2-one; Macrolide Aminoglycoside Derivative; 1-Azacyclotetradecan-2-one, 10-[(4-amino-4,6-dideoxy-α-D-mannopyranosyl)oxy]-3,11-diethyl-7-methyl-, (3S,7R,10R,11R)-; Complex Macrolide Glycoside; Stereoisomeric Macrolactam Glycoside; Advanced Chiral Intermediate CAS 128563-23-5
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) detailing all critical parameters, supporting use in cGMP and research applications. Specifications can be aligned with customer requirements for specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.