Description

4-(5,5-Dimethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is a high-purity, versatile boronic ester derivative featuring a reactive aldehyde functional group. This compound is a critical building block in modern synthetic organic chemistry, enabling the efficient construction of complex molecular architectures through cross-coupling and subsequent functionalization. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel biaryl compounds with potential therapeutic activity.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the boronate group for efficient carbon-carbon bond formation.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs or OFETs, where the aldehyde allows for further conjugation extension.
• Chemical Biology Probes: Utilized to create tagged molecules or bioconjugates for studying biological processes, as the aldehyde can be used for site-specific labeling.
• Custom Synthesis and Contract Manufacturing: An essential reagent for custom synthesis houses serving the life sciences industry, providing tailored intermediates for client projects.

Basic Information

Product Name	4-(5,5-Dimethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde
CAS No.	128376-65-8
Molecular Formula	C11H13BO3
Molecular Weight	204.03 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; 4-Formylphenylboronic acid pinacol ester; 4-(Pinacolatoboryl)benzaldehyde; 4-Aldehydephenylboronic acid pinacol ester; 4-Boronobenzaldehyde pinacol ester; p-Formylphenylboronic acid pinacol ester; Benzaldehyde, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 4-(5,5-Dimethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistent performance for sensitive cross-coupling reactions. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.