Description

Cyclopropanecarboxylic Acid, 2-Fluoro-1-Methyl-, Ethyl Ester, trans- (9Ci) is a high-purity fluorinated cyclopropane derivative, a crucial chiral building block in advanced organic synthesis. Its value lies in the unique reactivity and stereochemistry imparted by the cyclopropane ring and fluorine atom, enabling the construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of new active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorinated cyclopropane moiety can enhance biological activity and environmental stability.
• Asymmetric Synthesis: Serves as a versatile precursor in catalytic asymmetric reactions to introduce the sterically constrained and stereodefined cyclopropane unit into target molecules.
• Material Science Research: Investigated as a monomer or modifier for creating specialty polymers with unique thermal or chemical resistance properties.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring the effects of fluorine substitution on molecular conformation and reactivity.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-Fluoro-1-Methyl-, Ethyl Ester, trans- (9Ci)
CAS No.	128230-92-2
Molecular Formula	C7H11FO2
Molecular Weight	146.16 g/mol
Synonyms	trans-Ethyl 2-Fluoro-1-methylcyclopropanecarboxylate; Ethyl (1R,2S)-2-Fluoro-1-methylcyclopropanecarboxylate; Ethyl (1S,2R)-2-Fluoro-1-methylcyclopropanecarboxylate; 2-Fluoro-1-methylcyclopropanecarboxylic Acid Ethyl Ester; trans-2-Fluoro-1-methylcyclopropanecarboxylic Acid Ethyl Ester; Fluoromethylcyclopropanecarboxylic Acid Ethyl Ester; (1R,2S)-rel-2-Fluoro-1-methylcyclopropanecarboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-Fluoro-1-Methyl-, Ethyl Ester, trans- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥97.0%
Enantiomeric Excess (Chiral HPLC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.