Description

Cyclopropanecarboxamide, 2,2-Difluoro-1-Methyl- (9Ci) is a high-purity, specialized fluorinated cyclopropane derivative identified by CAS No. 128230-75-1. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the difluorocyclopropane moiety can enhance biological activity and metabolic stability.
• Organic Synthesis Building Block: Employed in medicinal chemistry and material science for introducing the sterically constrained, fluorinated cyclopropane ring system into target molecules.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring the properties and reactivity of fluorinated small rings.

Basic Information

Item	Detail
Product Name	Cyclopropanecarboxamide, 2,2-Difluoro-1-Methyl- (9Ci)
CAS No.	128230-75-1
Molecular Formula	C5H7F2NO
Molecular Weight	135.11 g/mol
Synonyms	2,2-Difluoro-1-methylcyclopropanecarboxamide; 1-Methyl-2,2-difluorocyclopropanecarboxamide; 2,2-Difluoro-1-methylcyclopropanecarboxylic acid amide; (2,2-Difluoro-1-methylcyclopropyl)formamide; Difluoromethylcyclopropanecarboxamide; 128230-75-1; 9CI compound
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxamide, 2,2-Difluoro-1-Methyl- (9Ci) adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and lot-to-lot consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.