Description

2,2-Difluoro-1-Methylcyclopropane Carboxylic Acid is a specialized fluorinated cyclopropane derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a cyclopropane ring with fluorine and carboxylic acid functional groups, makes it a valuable precursor for creating complex molecules with tailored properties. This high-purity intermediate is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to introduce fluorinated cyclopropane motifs into active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting metabolic diseases and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorinated cyclopropane unit can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced materials with unique surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel chiral ligands and catalysts for asymmetric synthesis.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research exploring the effects of fluorine substitution on molecular conformation and reactivity.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical manufacturers for use in custom synthesis projects and scale-up campaigns for client-specific molecules.

Basic Information

Product Name	2,2-Difluoro-1-Methylcyclopropane Carboxylic Acid
CAS No.	128073-33-6
Molecular Formula	C5H6F2O2
Molecular Weight	136.10 g/mol
Synonyms	1-Methyl-2,2-difluorocyclopropanecarboxylic Acid; 2,2-Difluoro-1-methylcyclopropanecarboxylic Acid; 2,2-Difluoro-1-methylcyclopropane-1-carboxylic Acid; Difluoromethylcyclopropanecarboxylic Acid; (1-Methyl-2,2-difluorocyclopropyl)formic Acid; DFMCPA
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-1-Methylcyclopropane Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, ensure containers are made of compatible materials and are properly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.