Description

Ethanone, 1-(2,2-Difluoro-1-Methylcyclopropyl)- (9Ci) is a specialized fluorinated ketone building block, identified by CAS number 128073-32-5, prized for its unique difluorocyclopropyl moiety which imparts distinct electronic and steric properties. This compound is critical for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals where the introduction of fluorine atoms is a key strategy to modulate bioactivity and metabolic stability. It serves as a high-value intermediate for medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate complex fluorinated motifs.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, especially in antiviral, anti-inflammatory, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides where fluorination enhances efficacy and environmental profile.
• Advanced Material Precursor: Serves as a building block for fluorinated polymers, liquid crystals, and specialty coatings requiring specific thermal and chemical resistance.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex molecular architectures via reactions like cycloadditions or as a directing group.
• Fluorine Chemistry Research: An essential compound for studying the effects of gem-difluoro groups on cyclopropane ring strain and reactivity.

Basic Information

Product Name	Ethanone, 1-(2,2-Difluoro-1-Methylcyclopropyl)- (9Ci)
CAS No.	128073-32-5
Molecular Formula	C6H8F2O
Molecular Weight	134.13 g/mol
Synonyms	1-(2,2-Difluoro-1-methylcyclopropyl)ethanone; 2,2-Difluoro-1-methylcyclopropyl methyl ketone; 1-Acetyl-2,2-difluoro-1-methylcyclopropane; 2,2-Difluoro-1-methyl-1-acetylcyclopropane; α,α-Difluoro-γ-methyl-γ-butyrolactone precursor; DFMCP Ketone
EINECS	Contact for details

Quality Control

Every batch of Ethanone, 1-(2,2-Difluoro-1-Methylcyclopropyl)- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.