Description

1-tert-Butyl-1H-Pyrazole-4-Carbaldehyde is a versatile and high-value pyrazole derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its reactive aldehyde group and the sterically hindered tert-butyl substituent, which are essential for constructing complex molecular architectures. This compound is particularly sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of new-generation pesticides, herbicides, and fungicides, leveraging its pyrazole core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, photoactive compounds, and other functional organic materials.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	1-tert-Butyl-1H-Pyrazole-4-Carbaldehyde
CAS No.	127949-06-8
Molecular Formula	C8H12N2O
Molecular Weight	152.20 g/mol
Synonyms	1-(1,1-Dimethylethyl)-1H-pyrazole-4-carboxaldehyde; 1-(tert-Butyl)-1H-pyrazole-4-carbaldehyde; 4-Formyl-1-tert-butylpyrazole; 1-tert-Butylpyrazole-4-carboxaldehyde; 1-tert-Butyl-1H-4-pyrazolecarboxaldehyde; 1-(tert-Butyl)-4-formylpyrazole; 1-Boc-Pyrazole-4-carbaldehyde (common abbreviation); 4-Carbaldehyde-1-tert-butylpyrazole
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl-1H-Pyrazole-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive. Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.