Description

(1R,2S)-7-Methyl-1,2-Dihydronaphthalene-1,2-Diol is a chiral dihydrodiol derivative of naphthalene, serving as a valuable synthetic intermediate and building block in advanced organic synthesis. Its stereochemically defined structure makes it a critical precursor for the development of pharmaceuticals, agrochemicals, and specialty materials. This compound is particularly relevant for research chemists and process development scientists in the pharmaceutical and fine chemical industries seeking to construct complex, optically active molecules.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of stereoselective drugs.
• Agrochemical Synthesis: Used in the research and production of advanced, optically active pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or precursor for the synthesis of novel polymers and advanced organic materials.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in chiral analysis.

Basic Information

Product Name	(1R,2S)-7-Methyl-1,2-Dihydronaphthalene-1,2-Diol
CAS No.	127926-10-7
Molecular Formula	C11H12O2
Molecular Weight	176.21 g/mol
Synonyms	(1R,2S)-7-Methyl-1,2-dihydronaphthalene-1,2-diol; 7-Methyl-1,2-dihydronaphthalene-1,2-diol, (1R,2S)-; (1R,2S)-7-Methyl-1,2-naphthalenediol (dihydro); 1,2-Dihydro-7-methylnaphthalene-1,2-diol, (1R,2S)-; Chiral 7-Methyl Dihydrodiol; (1R,2S)-1,2-Dihydroxy-7-methyl-1,2-dihydronaphthalene
EINECS	Contact for details

Quality Control

Our (1R,2S)-7-Methyl-1,2-Dihydronaphthalene-1,2-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% de
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.