Description

Ethanone, 2,2-Dichloro-1-(3-Fluorophenyl)- (9Ci) is a specialized halogenated aromatic ketone building block, identified by CAS number 127728-55-6. This compound is valued for its unique molecular scaffold, which is critical for introducing dichloroacetyl and fluorophenyl motifs into advanced chemical syntheses. It serves as a key intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the dichloroacetyl group for enhanced biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocycles and fluorinated compounds via reactions like Friedel-Crafts acylation and nucleophilic substitution.
• Ligand and Catalyst Development: The fluorophenyl and carbonyl groups make it a candidate for developing novel ligands in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Ethanone, 2,2-Dichloro-1-(3-Fluorophenyl)- (9Ci)
CAS No.	127728-55-6
Molecular Formula	C8H5Cl2FO
Molecular Weight	207.03 g/mol
Synonyms	2,2-Dichloro-1-(3-fluorophenyl)ethanone; 3-Fluorophenyldichloroacetyl; 1-(3-Fluorophenyl)-2,2-dichloroethanone; α,α-Dichloro-3-fluoroacetophenone; 3-Fluorodichloroacetophenone; Dichloro(3-fluorophenyl)methanone; (3-Fluorophenyl)dichloromethyl ketone
EINECS	Contact for details

Quality Control

Our production of Ethanone, 2,2-Dichloro-1-(3-Fluorophenyl)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.