Description

Methyl 2-(4-Bromophenyl)-2-Hydroxyacetate is a versatile chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its structure, featuring both a bromoaryl group and a protected α-hydroxy ester moiety, makes it a valuable precursor for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of potential drug candidates, including non-steroidal anti-inflammatory agents and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the 4-bromophenyl group for structural diversity.
• Ligand and Catalyst Preparation: Serves as a starting material for the development of chiral ligands used in asymmetric catalysis.
• Fine Chemical Production: Employed in custom synthesis and the manufacture of specialty chemicals for material science and electronics.
• Academic and R&D: A valuable compound for methodological studies in organic chemistry, particularly in cross-coupling reactions and ester chemistry.

Basic Information

Product Name	Methyl 2-(4-Bromophenyl)-2-Hydroxyacetate
CAS No.	127709-20-0
Molecular Formula	C9H9BrO3
Molecular Weight	245.07 g/mol
Synonyms	Methyl (4-Bromophenyl)(hydroxy)acetate; 2-Hydroxy-2-(4-bromophenyl)acetic Acid Methyl Ester; Methyl α-Hydroxy-4-bromophenylacetate; 4-Bromomandelic Acid Methyl Ester; Methyl 4-Bromomandelate; (4-Bromophenyl)(hydroxy)acetic acid methyl ester; Methyl 2-hydroxy-2-(4-bromophenyl)acetate
EINECS	Contact for details

Quality Control

Our Methyl 2-(4-Bromophenyl)-2-Hydroxyacetate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment. We adhere to cGMP standards where applicable to meet the stringent requirements of our global pharmaceutical and research clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.