Description

1-(2,2,2-Trifluoroethoxysulfonyl)Ethane is a specialized organosulfur and organofluorine compound, identified by CAS NO 127649-10-9, serving as a valuable synthetic intermediate. Its unique structure, featuring a sulfonyl group adjacent to a trifluoroethoxy moiety, makes it a critical reagent for introducing fluorinated sulfonate or sulfonamide functionalities into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of protease inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in creating advanced herbicides and pesticides with improved environmental profiles and efficacy.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers with unique surface properties.
• Ligand and Catalyst Development: Employed in the design of fluorinated ligands for catalysis and molecular recognition applications.
• Chemical Biology Probes: Utilized to create activity-based probes for studying enzyme function and mechanism.
• Fluorinated Surfactant Precursor: Acts as a starting material for synthesizing high-performance, fluorinated surfactants and surface modifiers.

Basic Information

Product Name	1-(2,2,2-Trifluoroethoxysulfonyl)Ethane
CAS No.	127649-10-9
Molecular Formula	C4H7F3O3S
Molecular Weight	192.16 g/mol
Synonyms	Ethane, 1-(2,2,2-trifluoroethoxysulfonyl)-; 2,2,2-Trifluoroethyl ethanesulfonate; Ethanesulfonic acid, 2,2,2-trifluoroethyl ester; 1-(Trifluoroethoxysulfonyl)ethane; TFESE; Trifluoroethyl ethanesulfonate
EINECS	Contact for details

Quality Control

Our production of 1-(2,2,2-Trifluoroethoxysulfonyl)Ethane adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong bases and fluorides; keep away from incompatible materials. For long-term storage, consider using an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.