Description

[(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl]Palladium(II) Chloride is a high-purity, chiral palladium complex widely recognized as a premier catalyst for asymmetric synthesis. Its value lies in enabling highly enantioselective cross-coupling and hydrogenation reactions, which are critical for producing single-isomer pharmaceutical intermediates and fine chemicals. This product is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance catalysts to streamline complex synthetic routes.

Application

• As a precatalyst or catalyst precursor for asymmetric Suzuki-Miyaura and Negishi cross-coupling reactions.
• Enabling enantioselective hydrogenation of prochiral olefins and ketones in pharmaceutical intermediate synthesis.
• Catalyzing asymmetric allylic alkylation (AAA) reactions for the construction of chiral carbon centers.
• Use in academic and industrial R&D for developing novel catalytic methodologies in organic synthesis.
• Production of optically active ligands and complexes for further catalytic applications.
• Key component in process chemistry for the scalable manufacture of chiral active pharmaceutical ingredients (APIs).

Basic Information

Item	Detail
Product Name	[(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl]Palladium(II) Chloride
CAS No.	127593-28-6
Molecular Formula	C44H32Cl2P2Pd
Molecular Weight	804.93 g/mol
Synonyms	(R)-BINAP-PdCl2; (R)-(+)-BINAP Palladium(II) Chloride; Pd[(R)-BINAP]Cl2; (R)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl palladium dichloride; (R)-BINAP-PdCl2 Complex; (R)-BINAP Pd(II) Chloride; Palladium(II) (R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl Chloride
EINECS	Contact for details

Quality Control

Our [(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl]Palladium(II) Chloride is manufactured under controlled conditions to ensure batch-to-batch consistency and high catalytic activity. Each lot undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification. Certificates of Analysis (COA) detailing purity, metal content, and chiral purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent decomposition. The material is light-sensitive and easily oxidized; prolonged exposure to air, moisture, or ambient light should be avoided.

Specification

Item	Specification
Appearance	Orange to red-brown powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Pd Content	12.0 - 14.0 %
Specific Rotation [α]D20	+220° to +250° (c=0.1 in CHCl3)
Solubility	Soluble in chlorinated solvents, DCM, chloroform

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.