Description

n-(4-Chloro-2-Formylphenyl)-2,2-Dimethylpropionamide is a specialized organic intermediate featuring a unique molecular scaffold combining a formyl group with a pivalamide moiety on a chlorinated benzene ring. This compound matters for its role as a critical building block in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, or insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, or organic electronic materials due to its rigid, functionalized structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function or cellular pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Item	Detail
Product Name	n-(4-Chloro-2-Formylphenyl)-2,2-Dimethylpropionamide
CAS No.	127472-35-9
Molecular Formula	C14H16ClNO2
Molecular Weight	265.74 g/mol
Synonyms	4-Chloro-2-(2,2-dimethylpropanamido)benzaldehyde; Pivaloyl-4-chloroanthranilaldehyde; 2-Formyl-5-chloro-N-pivaloylaniline; 5-Chloro-2-pivalamidobenzaldehyde; N-(4-Chloro-2-formylphenyl)pivalamide; 2-Amino-5-chlorobenzaldehyde pivalamide derivative; 127472-35-9; 4-Chloro-2-pivalamidobenzaldehyde
EINECS	Contact for details

Quality Control

Every batch of n-(4-Chloro-2-Formylphenyl)-2,2-Dimethylpropionamide is produced under a strict quality management system. We ensure compliance with relevant industry standards through rigorous in-process and final release testing. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.