Description

5-Bromo-4-Fluoroindan-1-One is a high-purity, synthetically valuable halogenated indanone derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a building block for electron-transport or host materials in the development of advanced display and lighting technologies.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Chemical Research & Development: Serves as a standard or starting material in academic and industrial R&D for exploring new organic reactions and methodologies.
• Fluorescent Probe and Sensor Development: Utilized in the design of molecular probes for bioimaging and chemical sensing applications due to its halogenated aromatic structure.

Basic Information

Product Name	5-Bromo-4-Fluoroindan-1-One
CAS No.	127425-74-5
Molecular Formula	C9H6BrFO
Molecular Weight	229.05 g/mol
Synonyms	5-Bromo-4-fluoro-2,3-dihydro-1H-inden-1-one; 4-Fluoro-5-bromoindan-1-one; 1H-Inden-1-one, 5-bromo-4-fluoro-2,3-dihydro-; 5-Bromo-4-fluoroindanone; 127425-74-5; 5-Br-4-F-indan-1-one
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Fluoroindan-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.