Description

Frondoside A Hydrate is a bioactive triterpenoid glycoside primarily isolated from sea cucumbers. This compound matters due to its significant and well-documented pharmacological properties, including potent anti-inflammatory, anti-cancer, and immunomodulatory activities. It is a critical research-grade material needed by pharmaceutical R&D teams, academic institutions, and biotechnology companies for drug discovery, preclinical studies, and investigating novel therapeutic pathways.

Application

• Pharmaceutical Research & Drug Discovery: A key reference standard and active pharmaceutical ingredient (API) intermediate for developing novel anti-cancer and anti-inflammatory therapeutics.
• Preclinical & Biological Studies: Used in in vitro and in vivo models to study mechanisms of apoptosis, metastasis inhibition, and immune system modulation.
• Biochemical & Pharmacological Assays: Serves as a high-purity standard for assay development, validation, and screening in high-throughput platforms.
• Academic Research: Essential for universities and research institutes exploring marine natural products, cancer biology, and inflammatory disease mechanisms.
• Nutraceutical & Cosmetic R&D: Investigated for potential applications in advanced skincare (anti-aging, anti-inflammatory) and functional food supplements.

Basic Information

Product Name	Frondoside A Hydrate
CAS No.	127367-76-4
Molecular Formula	C54H85NaO26S · xH2O
Molecular Weight	~1181.3 (Anhydrous basis)
Synonyms	Frondoside A; Frondoside A Monohydrate; Cucumarioside A2; Holothurin A2; (3β,12α)-3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-12-hydroxylanosta-7,24-dien-21-oic Acid O-6-Deoxy-α-L-galactopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→4)-[β-D-xylopyranosyl-(1→2)]-β-D-quinovopyranosyl Ester Sodium Salt; Sodium Frondoside A; Sea Cucumber Saponin A
EINECS	Contact for details

Quality Control

Our Frondoside A Hydrate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and MS for identity. A detailed Certificate of Analysis (COA) is provided, confirming compliance with in-house specifications tailored for pharmaceutical research standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccant and under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.