Description

(5E)-5-(1H-Indol-3-Ylmethylidene)-2-Methyl-3-[5-[2-[(3-Nitrophenyl)Amino]Acetyl]Sulfanyl-1,3,4-Thiadiazol-2-Yl]Imidazol-4-One is a sophisticated heterocyclic compound featuring a unique molecular architecture combining indole, imidazolone, and thiadiazole pharmacophores. This complex structure makes it a valuable advanced pharmaceutical intermediate for research and development in medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly for targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new bioactive molecules due to its multifunctional scaffold.
• Biochemical Probe Development: Acts as a precursor for creating specialized probes to study enzyme interactions or cellular pathways.
• Organic Synthesis Reference Standard: Employed as a high-purity standard for analytical method development and validation in QC laboratories.
• Contract Research & Manufacturing (CRAM): Supplied to organizations engaged in custom synthesis and development of proprietary compounds.

Basic Information

Item	Details
Product Name	(5E)-5-(1H-Indol-3-Ylmethylidene)-2-Methyl-3-[5-[2-[(3-Nitrophenyl)Amino]Acetyl]Sulfanyl-1,3,4-Thiadiazol-2-Yl]Imidazol-4-One
CAS No.	127227-41-2
Molecular Formula	C23H17N7O4S2
Molecular Weight	519.55 g/mol
Synonyms	5-(1H-Indol-3-ylmethylene)-2-methyl-3-[5-[[2-[(3-nitrophenyl)amino]-2-oxoethyl]thio]-1,3,4-thiadiazol-2-yl]-4(5H)-imidazolone; (5E)-5-(1H-Indol-3-ylmethylidene)-2-methyl-3-{5-[(2-{[(3-nitrophenyl)amino]acetyl})sulfanyl]-1,3,4-thiadiazol-2-yl}-1,3-imidazol-4-one; 127227-41-2; Thiadiazolyl imidazolone derivative; Indole-thiadiazole conjugate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced intermediates. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange solid powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.