Description

1,3-Dioxolane-4-Carboxylicacid,2,2,5-Trimethyl-,(4S-Trans)-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in its unique dioxolane-protected carboxylic acid functionality, which is crucial for constructing complex molecular architectures with precise stereochemical control. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), chiral catalysts, and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Employed as a building block for constructing complex, enantiomerically pure molecules in medicinal chemistry and total synthesis projects.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, including advanced ligands, catalysts, and fragrances requiring specific stereochemistry.
• Academic & Industrial Research: Serves as a valuable reagent in R&D laboratories for exploring new synthetic methodologies and chemical transformations.
• Agrochemical Development: Potential application as an intermediate in the synthesis of chiral agrochemicals and plant protection agents.

Basic Information

Product Name	1,3-Dioxolane-4-Carboxylicacid,2,2,5-Trimethyl-,(4S-Trans)-(9Ci)
CAS No.	127062-02-6
Molecular Formula	C7H12O4
Molecular Weight	160.17 g/mol
Synonyms	(4S-trans)-2,2,5-Trimethyl-1,3-dioxolane-4-carboxylic acid; (4S,5R)-2,2,5-Trimethyl-1,3-dioxolane-4-carboxylic acid; 2,2,5-Trimethyl-1,3-dioxolane-4-carboxylic acid, (4S-trans)-; (4S,5R)-2,2,5-Trimethyl-[1,3]dioxolane-4-carboxylic acid; L-Threonic acid 2,3-acetonide; (4S,5R)-2,2,5-Trimethyl-1,3-dioxolane-4-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Carboxylicacid,2,2,5-Trimethyl-,(4S-Trans)-(9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification, to meet the exacting standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.