Description

Fmoc-D-Ala-Aldehyde CAS NO 127043-32-7 is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound serves as a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled introduction of D-alanine residues with an aldehyde functional handle. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptide-based therapeutics, diagnostics, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of D-alanine in peptide chains.
• Pharmaceutical Research: Building block for the development of peptide drugs, antimicrobial peptides (AMPs), and hormone analogs.
• Bioconjugation: The aldehyde group facilitates site-specific labeling and conjugation with proteins, antibodies, or other biomolecules.
• Chemical Biology Probes: Used in the synthesis of activity-based probes and inhibitors for studying enzyme function.
• Combinatorial Chemistry: Valuable for generating diverse peptide libraries for drug discovery screening.
• Material Science: Precursor for creating peptide-based polymers and biomimetic materials.

Basic Information

Product Name	Fmoc-D-Ala-Aldehyde
CAS No.	127043-32-7
Molecular Formula	C₁₉H₁₉NO₄
Molecular Weight	325.36 g/mol
Synonyms	Fmoc-D-alaninal; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-alaninal; (R)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)propanal; Fmoc-D-Ala-H; Fmoc-D-Alanine aldehyde; N-Fmoc-D-alaninal; D-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, aldehyde
EINECS	Contact for details

Quality Control

Our Fmoc-D-Ala-Aldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO, Acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.