Description

1,3-Dioxolane, 2-(Chloromethyl)-4,4-Dimethyl- is a versatile and highly functionalized heterocyclic building block, primarily valued for its reactive chloromethyl and acetal groups. This compound is crucial for the synthesis of complex molecules, enabling the introduction of protected aldehyde functionalities and serving as a key intermediate in advanced organic chemistry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for drug discovery, crop protection, and material science applications.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex heterocycles and active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer research.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its functional groups allow for the creation of novel bioactive structures.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for specialty polymers, including functional resins and coatings with tailored properties.
• Organic Synthesis Building Block: Employed in multi-step synthesis for the controlled introduction of aldehyde equivalents and other functional groups under mild conditions.
• Ligand and Catalyst Development: Useful in the preparation of novel chelating ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Investigated for creating novel organic frameworks and advanced materials with specific chemical functionalities.

Basic Information

Item	Detail
Product Name	1,3-Dioxolane, 2-(Chloromethyl)-4,4-Dimethyl-
CAS No.	126910-65-4
Molecular Formula	C6H11ClO2
Molecular Weight	150.60 g/mol
Synonyms	2-(Chloromethyl)-4,4-dimethyl-1,3-dioxolane; 4,4-Dimethyl-2-chloromethyl-1,3-dioxolane; 1,3-Dioxolane, 2-(chloromethyl)-4,4-dimethyl-; 2-(Chloromethyl)-4,4-dimethyl-[1,3]dioxolane; (Chloromethyl)acetaldehyde dimethyl acetal (cyclic); 4,4-Dimethyl-2-(chloromethyl)-1,3-dioxolane; Cyclic acetal of chloromethylacetaldehyde
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane, 2-(Chloromethyl)-4,4-Dimethyl- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography and spectroscopy, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Refractive Index (n20D)	1.430 - 1.440
Density (20°C)	1.08 - 1.12 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.