Description

Oxiranecarboxaldehyde, 3-Phenyl-, (2R,3S)- (9Ci) is a high-value, stereochemically defined chiral building block, specifically the (2R,3S) enantiomer of phenylglycidyl aldehyde. This compound matters as a versatile and critical intermediate for the asymmetric synthesis of complex molecules, enabling the introduction of both an aldehyde and an epoxide functional group with precise stereocontrol. Pharmaceutical, agrochemical, and advanced material researchers need it for developing novel active ingredients, chiral ligands, and specialty polymers where the defined three-dimensional structure is essential for function.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in oncology, antiviral, and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry enhances efficacy and reduces environmental impact.
• Chiral Ligand & Catalyst Preparation: Serves as a precursor for synthesizing sophisticated ligands used in asymmetric catalysis.
• Advanced Material Research: Employed in the development of specialty epoxy resins and polymers with tailored mechanical or optical properties.
• Fine Chemical Production: Integral to multi-step synthetic routes for flavors, fragrances, and other high-value specialty chemicals.
• Academic & R&D Laboratories: A valuable tool for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	Oxiranecarboxaldehyde, 3-Phenyl-, (2R,3S)- (9Ci)
CAS No.	126720-47-6
Molecular Formula	C10H10O2
Molecular Weight	162.19 g/mol
Synonyms	(2R,3S)-3-Phenylglycidaldehyde; (2R,3S)-Phenylglycidyl Aldehyde; (2R,3S)-2,3-Epoxy-3-phenylpropanal; (2R,3S)-3-Phenyloxiranecarboxaldehyde; trans-3-Phenylglycidaldehyde (specific isomer); (2R,3S)-3-Phenyl-1,2-epoxypropan-1-al; (R*,S*)-3-Phenylglycidaldehyde
EINECS	Contact for details

Quality Control

Our production of Oxiranecarboxaldehyde, 3-Phenyl-, (2R,3S)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. All material is characterized by advanced analytical techniques including chiral HPLC, GC, NMR, and IR spectroscopy. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment. We support cGMP manufacturing standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and volatility. The container should be kept in a cool, dry, well-ventilated area, separate from incompatible materials. Allow the container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.