Description

2-(Trimethylsilyl)Vinylboronic Acid Pinacol Ester is a high-value organoboron reagent featuring a protected vinylboronate group and a trimethylsilyl (TMS) moiety. This compound is a critical building block in modern synthetic chemistry, enabling efficient carbon-carbon bond formation through cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for introducing vinyl groups into complex molecules, widely used in pharmaceutical intermediate synthesis.
• Agrochemical Active Ingredient Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides requiring specific vinyl-substituted structures.
• Advanced Material & OLED Precursor Synthesis: Used to create conjugated organic molecules and polymers for electronic and optoelectronic applications.
• Natural Product and Fine Chemical Synthesis: Facilitates the stereoselective construction of challenging carbon frameworks in complex natural products.
• Library Synthesis for Drug Discovery: Enables high-throughput parallel synthesis of diverse compound libraries for biological screening.
• Functionalized Silane Derivative Production: Serves as a precursor for other functional organosilicon compounds.

Basic Information

Item	Detail
Product Name	2-(Trimethylsilyl)Vinylboronic Acid Pinacol Ester
CAS No.	126688-99-1
Molecular Formula	C13H27BO2Si
Molecular Weight	254.25 g/mol
Synonyms	2-(Trimethylsilyl)ethenylboronic acid pinacol ester; (2-(Trimethylsilyl)vinyl)boronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-[2-(trimethylsilyl)ethenyl]-1,3,2-dioxaborolane; Vinylboronic acid pinacol ester, 2-(trimethylsilyl)-; TMS-vinylBPin; 2-Trimethylsilylvinylboronic Acid Pinacol Ester; 2-(Trimethylsilyl)vinylboronate Pinacol Ester
EINECS	Contact for details

Quality Control

Our 2-(Trimethylsilyl)Vinylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B) and GC/HPLC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full specification data are provided to guarantee batch-to-batch consistency and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air or ambient conditions should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.