Description

2-((E)-5-Chloropent-1-Enyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is valued for its role as a key precursor in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific chloropentenyl motifs.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a probe or linker in bioconjugation and target identification studies.
• Organic Synthesis Reagent: Facilitates the introduction of the 5-chloropent-1-enyl group into complex organic molecules under mild conditions.
• Liquid Crystal & OLED Material Precursor: Used in the synthesis of specialized organic compounds for display and lighting technologies.

Basic Information

Product Name	2-((E)-5-Chloropent-1-Enyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	126688-98-0
Molecular Formula	C11H20BClO2
Molecular Weight	230.54 g/mol
Synonyms	(E)-5-Chloro-1-penten-1-ylboronic acid pinacol ester; (E)-5-Chloropent-1-en-1-ylboronic Acid Pinacol Ester; 2-[(1E)-5-Chloro-1-penten-1-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Chloro-1-penten-1-ylboronic Acid Pinacol Ester; (E)-5-Chloropentenylboronic Acid Pinacol Ester; Pinacol (E)-5-Chloropent-1-en-1-ylboronate
EINECS	Contact for details

Quality Control

Our 2-((E)-5-Chloropent-1-Enyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, isomeric purity, and impurity profiles. Our quality system is designed to support cGMP compliance for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Isomeric Purity (E/Z Ratio by GC/HPLC)	≥ 95:5 (E:Z)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.