Description

2-Bromo-1-(5-Fluoro-2-Hydroxyphenyl)Ethanone is a specialized brominated aromatic ketone derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromo and fluoro substituents on a hydroxyphenyl core, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the creation of fluorescent tags and molecular probes for studying biological pathways and enzyme activity.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry laboratories and contract research organizations (CROs).

Basic Information

Product Name	2-Bromo-1-(5-Fluoro-2-Hydroxyphenyl)Ethanone
CAS No.	126581-65-5
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethan-1-one; 1-(5-Fluoro-2-hydroxyphenyl)-2-bromoethanone; 2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone; 5'-Fluoro-2'-hydroxy-2-bromoacetophenone; 2-Bromo-5'-fluoro-2'-hydroxyacetophenone; α-Bromo-5-fluoro-2-hydroxyacetophenone; 126581-65-5
EINECS	Contact for details

Quality Control

Our production of 2-Bromo-1-(5-Fluoro-2-Hydroxyphenyl)Ethanone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, IR) to verify identity, potency, and impurity profiles. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our facilities operate under cGMP principles where applicable, ensuring traceability and compliance for demanding pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent photodegradation. For long-term storage, consider under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.