Description

3-(2-Chlorophenyl)-1H-Pyrazol-5-Amine CAS NO 126520-01-2 is a versatile pyrazole derivative, a key organic intermediate prized for its role in constructing complex molecular architectures. Its primary value lies in its bifunctional amine and heterocyclic structure, making it an essential building block for pharmaceutical and agrochemical research and development. This compound is particularly sought after by R&D chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a core scaffold for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Used in organometallic chemistry to create specialized ligands for catalytic systems and metal-organic frameworks (MOFs).
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of advanced colorants and functional dyes.
• Material Science Research: Employed in the synthesis of organic semiconductors, polymers, and other advanced materials requiring specific heterocyclic components.
• Academic and Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting exploratory synthetic chemistry and medicinal chemistry programs.

Basic Information

Item	Detail
Product Name	3-(2-Chlorophenyl)-1H-Pyrazol-5-Amine
CAS No.	126520-01-2
Molecular Formula	C9H8ClN3
Molecular Weight	193.63 g/mol
Synonyms	5-Amino-3-(2-chlorophenyl)-1H-pyrazole; 3-(2-Chlorophenyl)-1H-pyrazol-5-amine; 2-Chloro-α-(aminomethylidene)benzeneacetonitrile; 1H-Pyrazol-5-amine, 3-(2-chlorophenyl)-; 5-Amino-3-(o-chlorophenyl)pyrazole; 3-(2-Chlorophenyl)-5-aminopyrazole; (2-Chlorophenyl)((1H-pyrazol-5-yl)amino)methanimine
EINECS	Contact for details

Quality Control

Our production of 3-(2-Chlorophenyl)-1H-Pyrazol-5-Amine adheres to stringent in-process controls and final batch testing to ensure consistent purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality management system is designed to support cGMP (current Good Manufacturing Practice) standards for advanced intermediates, ensuring traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.