Description

(S)-tert-Butyl Methyl Aziridine-1,2-Dicarboxylate CAS NO 126496-79-5 is a high-purity, chiral aziridine derivative serving as a critical building block in asymmetric synthesis. Its value lies in providing a stereochemically defined, protected nitrogen-containing three-membered ring, enabling the efficient construction of complex molecules with precise stereocontrol. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), natural products, and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of nitrogen-containing drug candidates, including antibiotics, antivirals, and enzyme inhibitors.
• Asymmetric Synthesis: Used in ring-opening reactions and nucleophilic additions to introduce chiral amine functionalities with high enantioselectivity.
• Agrochemical Research: Employed in the development of novel, stereospecific pesticides and herbicides.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in transition metal catalysis.
• Peptidomimetics & Amino Acid Derivatives: Facilitates the construction of constrained peptide analogs and non-proteinogenic amino acids.
• Academic & Process R&D: A valuable tool for methodological development in organic chemistry and scale-up process optimization.

Basic Information

Product Name	(S)-tert-Butyl Methyl Aziridine-1,2-Dicarboxylate
CAS No.	126496-79-5
Molecular Formula	C10H17NO4
Molecular Weight	215.25 g/mol
Synonyms	1,2-Dicarbomethoxy-N-tert-butylaziridine, (S)-; Methyl (S)-1-(tert-butoxycarbonyl)aziridine-2-carboxylate; (S)-1-(tert-Butoxycarbonyl)aziridine-2-carboxylic acid methyl ester; (S)-N-Boc-aziridine-2-carboxylic acid methyl ester; (S)-Boc-Azi-OMe; (2S)-1-[(2-Methylpropan-2-yl)oxycarbonyl]aziridine-2-carboxylic acid methyl ester; (S)-tert-Butyl 2-(methoxycarbonyl)aziridine-1-carboxylate
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl Methyl Aziridine-1,2-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, NMR, and GC/MS, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.