Description

5''-Hydroxycannabidiol Glucoside is a specialized cannabinoid glycoside, representing a significant metabolite of cannabidiol (CBD) formed through natural biosynthetic pathways. This compound is of high interest for its potential role in enhancing the bioavailability and metabolic stability of cannabinoid-based actives. It serves as a critical reference standard and a valuable synthetic intermediate for researchers and developers in the pharmaceutical, nutraceutical, and advanced cannabinoid synthesis sectors.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of cannabinoid metabolites in drug development and pharmacokinetic studies.
• Metabolite Research: Essential for investigating the metabolic pathways, bioavailability, and activity of cannabidiol and related compounds.
• Advanced Cannabinoid Synthesis: Acts as a key precursor or intermediate in the synthesis of novel, targeted cannabinoid derivatives with modified properties.
• Analytical Method Development: Serves as a critical calibrant for developing and validating HPLC, LC-MS, and other analytical methods in compliance laboratories.
• Nutraceutical R&D: Explored for the development of next-generation cannabinoid-based supplements with potentially improved absorption profiles.
• Biochemical Studies: Utilized in enzymatic and receptor-binding assays to study the interaction of glycosylated cannabinoids with biological systems.

Basic Information

Product Name	5''-Hydroxycannabidiol Glucoside
CAS No.	126371-03-7
Molecular Formula	C27H40O8
Molecular Weight	492.61 g/mol
Synonyms	5'-Hydroxycannabidiol glucoside; 5''-OH-CBD-glucoside; Cannabidiol metabolite glucuronide (related); 2-[(1R,6R)-3-Methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol β-D-glucopyranoside; 5'-Hydroxy-δ⁹-tetrahydrocannabinol glucoside (structural analog); CBD metabolite reference standard
EINECS	Contact for details

Quality Control

Our 5''-Hydroxycannabidiol Glucoside is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the container to reach room temperature before opening to minimize moisture condensation. The material should be handled in a controlled environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.