Description

3,4-Dimethoxy-1-Nitro-1,3,5(10)-Estratrien-17-One is a high-purity, synthetic steroid derivative with the CAS registry number 126291-41-6. This compound serves as a critical advanced intermediate in the research and development of novel pharmaceutical agents, particularly in the fields of endocrinology and oncology. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in the synthesis of complex steroid-based molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroidal drugs and therapeutic agents.
• Research Chemical: Used in academic and industrial laboratories for studying steroid receptor interactions and metabolic pathways.
• Process Development: Serves as a reference standard and starting material for optimizing synthetic routes in process chemistry.
• Biochemical Research: Employed in the development of assays and probes for investigating hormonal activity and signaling.
• Fine Chemical Synthesis: Utilized for the custom synthesis of specialized steroid derivatives for client-specific research programs.

Basic Information

Product Name	3,4-Dimethoxy-1-Nitro-1,3,5(10)-Estratrien-17-One
CAS No.	126291-41-6
Molecular Formula	C20H23NO5
Molecular Weight	357.40 g/mol
Synonyms	1-Nitro-3,4-dimethoxyestra-1,3,5(10)-trien-17-one; 17-Oxo-1-nitro-3,4-dimethoxyestra-1,3,5(10)-triene; 3,4-Dimethoxy-1-nitroestra-1,3,5(10)-trien-17-one; 1-Nitro-3,4-dimethoxy-1,3,5(10)-estratrien-17-one; Nitrated Estradiol Derivative; Aromatic Nitro Steroid Intermediate
EINECS	Contact for details

Quality Control

Our 3,4-Dimethoxy-1-Nitro-1,3,5(10)-Estratrien-17-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.