Description

3-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its fused cyclopentane-pyridine core, functionalized with a reactive chlorine atom, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where it serves as a key scaffold.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates targeting various therapeutic areas, including central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used as a building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand Synthesis: Serves as a starting material for creating novel ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Material Science: A potential monomer or precursor for creating specialized polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	3-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine
CAS No.	126215-93-8
Molecular Formula	C8H8ClN
Molecular Weight	153.61 g/mol
Synonyms	3-Chloro-5H-cyclopenta[b]pyridine; 3-Chloro-6,7-dihydro-5H-cyclopentapyridine; 3-Chlorocyclopentapyridine; 3-Chloro-5H-cyclopenta[2,1-b:3,4-b']dipyridine (incorrect but common mis-association); 126215-93-8; 3-Cl-5H-CPP; Cyclopenta[b]pyridine, 3-chloro-6,7-dihydro-5H-
EINECS	Contact for details

Quality Control

Our 3-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.