Description

4-Hydroxy-3-formyl-6-methylcoumarin is a functionalized coumarin derivative characterized by its reactive formyl and phenolic hydroxyl groups. This compound serves as a versatile and valuable chemical intermediate for the synthesis of more complex heterocyclic systems and active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, agrochemical manufacturers, and producers of advanced organic materials and dyes.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates with potential anticoagulant, anti-inflammatory, or antimicrobial activities.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the bioactivity of the coumarin core.
• Fluorescent Probe & Sensor Development: Serves as a precursor for creating sensitive chemosensors due to its inherent fluorophore properties that can be modified.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a starting material for synthesizing electron-transport or emissive layer components in display technologies.
• Dye & Pigment Manufacturing: Utilized in the production of specialized dyes and optical brighteners for textiles and polymers.
• Coordination Chemistry & Ligand Synthesis: The formyl and hydroxyl groups make it a useful precursor for creating chelating ligands for metal ions.
• Academic & Industrial Research: Employed in chemical research for studying reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	4-Hydroxy-3-formyl-6-methylcoumarin
CAS No.	126214-23-1
Molecular Formula	C11H8O4
Molecular Weight	204.18 g/mol
Synonyms	6-Methyl-4-hydroxycoumarin-3-carboxaldehyde; 3-Formyl-4-hydroxy-6-methylcoumarin; 4-Hydroxy-6-methyl-3-coumarincarboxaldehyde; 4-Hydroxy-6-methyl-2-oxo-2H-chromene-3-carbaldehyde; 4-Hydroxy-3-formyl-6-methyl-2H-chromen-2-one; 6-Methyl-4-hydroxy-2-oxo-2H-chromene-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-3-formyl-6-methylcoumarin is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets precise specifications. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.