Description

28-Deoxonimbolide is a specialized limonoid compound derived from natural sources, recognized for its distinct chemical structure and biological activity. This high-purity intermediate is critical for advanced research and development in the pharmaceutical and life sciences sectors, where precise molecular integrity is paramount. It serves as a valuable building block for medicinal chemists and researchers focused on oncology, anti-inflammatory, and other therapeutic areas requiring complex natural product analogs.

Application

• Pharmaceutical Research & Development: A key intermediate in the synthesis and study of novel therapeutic agents, particularly in oncology and anti-inflammatory drug discovery programs.
• Medicinal Chemistry: Used as a sophisticated scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization.
• Natural Product Chemistry: Serves as a reference standard or a starting material for the semi-synthesis of complex limonoids and related bioactive compounds.
• Biochemical Research: Employed in in-vitro assays to investigate specific biological pathways and mechanisms of action at the cellular level.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and natural product pharmacology.

Basic Information

Product Name	28-Deoxonimbolide
CAS No.	126005-94-5
Molecular Formula	C28H34O8
Molecular Weight	498.57 g/mol
Synonyms	28-Deoxonimbolide; Nimbolide derivative; Limonoid C28H34O8; (1S,2S,4R,5S,6R,7S,10S,11S,14R,15R,17S)-5,6,14,15-Tetrahydroxy-4,4,7,11,15-pentamethyl-3,16-dioxatetracyclo[10.3.1.0²,¹⁰.0⁵,⁹]heptadec-8-en-17-yl (2E)-2-methylbut-2-enoate
EINECS	Contact for details

Quality Control

Our 28-Deoxonimbolide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research applications. Each lot is accompanied by comprehensive analytical data, including HPLC chromatograms and spectroscopic evidence (NMR, MS). Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.