Description

3-Chloro-1,1-Diethoxy-Propan-2-Ol is a specialized chlorinated acetal derivative with significant utility as a versatile synthetic intermediate. Its bifunctional structure, featuring both a chloro and a hydroxyl group, makes it a valuable building block for constructing more complex molecules in fine chemical synthesis. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the preparation of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a chlorinated propylene oxide or glycidol backbone.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where its reactive sites allow for the introduction of specific functional groups.
• Fine Chemical Manufacturing: Serves as a precursor for dyes, pigments, and specialty polymers, enabling controlled chemical modifications.
• Academic & Industrial Research: Employed in organic chemistry research for developing new synthetic methodologies and exploring structure-activity relationships.
• Cross-Coupling Reactions: The chloro group can act as a handle for various metal-catalyzed coupling reactions to form carbon-carbon bonds.
• Epoxide Precursor: Can be utilized in the synthesis of substituted epoxides, which are important intermediates in organic synthesis.

Basic Information

Product Name	3-Chloro-1,1-Diethoxy-Propan-2-Ol
CAS No.	125781-03-5
Molecular Formula	C7H15ClO3
Molecular Weight	182.65 g/mol
Synonyms	2-(Chloromethyl)-2-ethoxy-1,3-dioxolane; 3-Chloro-1,1-diethoxy-2-propanol; 1,1-Diethoxy-3-chloro-2-propanol; 2-Propanol, 3-chloro-1,1-diethoxy-; Chloromethyl ethoxy dioxolane; Glycidol diethyl acetal, chlorinated; Acetaldehyde, (3-chloro-2-hydroxypropylidene) diethyl acetal
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-1,1-Diethoxy-Propan-2-Ol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the presence of ether and alcohol functional groups, it should be stored separately from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Gravity (20°C)	1.10 - 1.15
Refractive Index (n20D)	1.430 - 1.440

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.