Description

3',4'-Dichloro-2,2,2-Trifluoroacetophenone is a high-purity, halogenated acetophenone derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique molecular structure, which provides a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for enhanced bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic display technologies.
• Organic Synthesis Reagent: Employed in Friedel-Crafts acylation and other reactions to introduce the trifluoroacetyl moiety into aromatic systems.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.
• Specialty Polymer Modifier: Acts as a monomer or modifier in the synthesis of high-performance, fluorinated polymers with unique thermal and chemical resistance.

Basic Information

Product Name	3',4'-Dichloro-2,2,2-Trifluoroacetophenone
CAS No.	125733-43-9
Molecular Formula	C8H3Cl2F3O
Molecular Weight	243.01 g/mol
Synonyms	1-(3,4-Dichlorophenyl)-2,2,2-trifluoroethanone; 3,4-Dichloro-α,α,α-trifluoroacetophenone; 2,2,2-Trifluoro-1-(3,4-dichlorophenyl)ethanone; 3,4-Dichlorophenyl trifluoromethyl ketone; 3,4-Dichloro-ω,ω,ω-trifluoroacetophenone; 3,4-Dichloro-α,α,α-trifluoroacetophenone; 1-(3,4-Dichlorophenyl)-2,2,2-trifluoro-1-ethanone
EINECS	Contact for details

Quality Control

Our 3',4'-Dichloro-2,2,2-Trifluoroacetophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles. Our production adheres to cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.