Description

Palmitic Acid, Dl-Threo-2-(2,2-Dichloroacetamido)-3-Hydroxy-3-(p-Nitrophenyl)Propyl Ester (6Ci) is a specialized synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound, with CAS number 125637-16-3, is valued for its complex molecular architecture, which serves as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and fine chemical manufacturers engaged in the development of targeted therapeutic agents, particularly within antimicrobial and specialty drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and proprietary molecules.
• Antimicrobial Research: Serves as a precursor in the development of new antibiotic and antifungal agents, leveraging its dichloroacetamido functional group.
• Chemical Biology Probes: Used in medicinal chemistry to study enzyme interactions and structure-activity relationships (SAR) due to its nitro-phenyl and ester functionalities.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of high-value target compounds.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	Palmitic Acid, Dl-Threo-2-(2,2-Dichloroacetamido)-3-Hydroxy-3-(p-Nitrophenyl)Propyl Ester (6Ci)
CAS No.	125637-16-3
Molecular Formula	C27H42Cl2N2O6
Molecular Weight	561.54 g/mol
Synonyms	DL-Threo-2-(2,2-Dichloroacetamido)-3-hydroxy-3-(4-nitrophenyl)propyl palmitate; 6Ci Chloramphenicol Palmitate Analog; (R*,S*)-2-(2,2-Dichloroacetamido)-3-hydroxy-3-(4-nitrophenyl)propyl hexadecanoate; Chloramphenicol Palmitate Derivative; 1,3-Dihydroxy-1-(4-nitrophenyl)-2-(dichloroacetamido)propyl palmitate; Palmitic acid ester of DL-threo-2-amino-1-(4-nitrophenyl)-1,3-propanediol N-dichloroacetate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and purity suitable for research and development. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.