Description

2-Butanone, 1-Diazo-4-(2-Thioxo-1-Piperidinyl)- is a specialized diazo compound with a thiocarbonyl functional group, offering unique reactivity for advanced synthetic transformations. This high-value intermediate is critical for researchers and process chemists developing novel active pharmaceutical ingredients (APIs) and complex organic molecules. It is primarily utilized in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring precise carbon-carbon and carbon-heteroatom bond formation.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex heterocyclic compounds and novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its diazo functionality for structure diversification.
• Organic Synthesis Reagent: Employed in specialized reactions such as cyclopropanation, X-H insertion (C-H, O-H, N-H), and as a carbene precursor under thermal or photochemical conditions.
• Advanced Materials Research: Potential precursor for functionalized polymers or materials science applications where the introduction of specific piperidine-thione motifs is required.
• Academic & R&D Laboratories: Serves as a valuable tool for methodological development in organic synthesis and catalysis studies.

Basic Information

Item	Detail
Product Name	2-Butanone, 1-Diazo-4-(2-Thioxo-1-Piperidinyl)-
CAS No.	125627-64-7
Molecular Formula	C9H13N3OS
Molecular Weight	211.28 g/mol
Synonyms	1-Diazo-4-(2-thioxopiperidin-1-yl)butan-2-one; 4-(2-Thioxo-1-piperidinyl)-1-diazo-2-butanone; 1-Diazo-4-(2-thioxo-1-piperidinyl)-2-butanone; 2-Butanone, 1-diazo-4-(2-thioxo-1-piperidinyl)-; Diazo thioketone derivative of butanone; 4-(2-Thioxopiperidino)-1-diazo-2-butanone
EINECS	Contact for details

Quality Control

Our production of 2-Butanone, 1-Diazo-4-(2-Thioxo-1-Piperidinyl)- adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your quality management and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature and potential thermal instability characteristic of diazo compounds, prolonged exposure to light, heat, or strong oxidizers should be avoided. Keep container tightly sealed under an inert atmosphere if specified for optimal long-term stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical: 97-99%)
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.