Description

Proline, Propyl Ester (9Ci) is a specialized amino acid derivative, specifically the propyl ester of L-proline. This compound is valued for its role as a versatile chiral building block and protecting group in sophisticated organic synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptides, prodrugs, and other bioactive molecules. The product is supplied with a high level of purity to meet the stringent requirements of advanced chemical synthesis.

Application

• Pharmaceutical Intermediates: Serves as a key chiral synthon in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a protected proline derivative in solid-phase and solution-phase peptide synthesis to control stereochemistry.
• Prodrug Development: Acts as a promoiety to enhance the bioavailability and pharmacokinetic properties of therapeutic compounds.
• Asymmetric Synthesis: Employed as a catalyst or auxiliary in enantioselective reactions due to its chiral nature.
• Biochemical Research: Utilized in studies of enzyme mechanisms, protein structure, and metabolic pathways.
• Fine Chemical Synthesis: A building block for creating complex natural products, flavors, and fragrances.

Basic Information

Product Name	Proline, Propyl Ester (9Ci)
CAS No.	125511-34-4
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	L-Proline propyl ester; Propyl L-prolinate; (S)-Pyrrolidine-2-carboxylic acid propyl ester; 1-Propyl L-prolinate; Propan-1-yl L-prolinate; Proline propyl ester; 125511-34-4
EINECS	Contact for details

Quality Control

Our Proline, Propyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets high-purity standards suitable for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is compatible with strong acids and organic solvents but should be kept separate from incompatible materials. Keep container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.