Description

Cyclohexane, 2-Fluoro-4-Methyl-1-(1-Methylethyl)-, (1S,2R,4R)- (9Ci) is a high-purity, stereochemically defined fluorinated cyclohexane derivative. This compound serves as a valuable chiral building block and intermediate in advanced organic synthesis, particularly for introducing specific three-dimensional complexity into target molecules. It is primarily required by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the specific stereochemistry and fluorine atom enhance biological activity and environmental stability.
• Advanced Material Research: Serves as a precursor for liquid crystals, specialty polymers, and other functional materials that benefit from its rigid, fluorinated cyclohexane core.
• Catalyst & Ligand Development: Employed in the synthesis of chiral catalysts and ligands for asymmetric synthesis, enabling more efficient and selective chemical transformations.
• Flavor & Fragrance Chemistry: Potential intermediate for creating complex, stereospecific aroma molecules due to its unique structural features.
• Academic & Contract Research: A critical reagent for methodological studies in organic chemistry, particularly in fluorination chemistry and stereoselective synthesis.

Basic Information

Product Name	Cyclohexane, 2-Fluoro-4-Methyl-1-(1-Methylethyl)-, (1S,2R,4R)- (9Ci)
CAS No.	125425-47-0
Molecular Formula	C10H19F
Molecular Weight	158.26 g/mol
Synonyms	(1S,2R,4R)-2-Fluoro-4-methyl-1-(1-methylethyl)cyclohexane; (-)-trans-2-Fluoro-4-methyl-1-isopropylcyclohexane; (1S,2R,4R)-1-Isopropyl-2-fluoro-4-methylcyclohexane; 2-Fluoro-4-methyl-1-(1-methylethyl)cyclohexane, (1S,2R,4R)-; Fluorinated Isopropylmethylcyclohexane; Chiral Fluorocyclohexane Derivative; Stereoisomer of C10H19F
EINECS	Contact for details

Quality Control

Our Cyclohexane, 2-Fluoro-4-Methyl-1-(1-Methylethyl)-, (1S,2R,4R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by GC or HPLC, to ensure high stereochemical and chemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its fluoride/strong alkali reactivity profile, ensure segregation from such substances.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Chiral Purity (ee)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.