Description

7-Oxabicyclo[4.1.0]Heptane, 4-Ethynyl-1-Methyl-, [1S-(1Alpha,4Alpha,6Alpha)]- (9Ci) is a high-purity, stereochemically defined bicyclic oxirane derivative containing a reactive ethynyl group. This compound serves as a versatile and valuable chiral building block in advanced organic synthesis, enabling the construction of complex molecular architectures with precise stereochemical control. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and herbicides where specific stereochemistry is critical for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Building block for developing novel polymers, resins, or functional materials with tailored properties.
• Academic & Industrial R&D: Essential reagent in chemical research for methodology development and exploring new chemical spaces.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Item	Detail
Product Name	7-Oxabicyclo[4.1.0]Heptane, 4-Ethynyl-1-Methyl-, [1S-(1Alpha,4Alpha,6Alpha)]- (9Ci)
CAS No.	125356-12-9
Molecular Formula	C8H10O
Molecular Weight	122.16 g/mol
Synonyms	(1S,4S,6S)-4-Ethynyl-1-methyl-7-oxabicyclo[4.1.0]heptane; 4-Ethynyl-1-methyl-7-oxabicyclo[4.1.0]heptane, (1S,4S,6S)-; (-)-(1S,4S,6S)-4-Ethynyl-1-methyl-7-oxabicyclo[4.1.0]heptane; Chiral 4-ethynyl-1-methyl-7-oxabicyclo[4.1.0]heptane; (1S,4S,6S)-4-Ethynyl-1-methyloxepane; Optically active oxirane-ethynyl building block
EINECS	Contact for details

Quality Control

Every batch of 7-Oxabicyclo[4.1.0]Heptane, 4-Ethynyl-1-Methyl-, [1S-(1Alpha,4Alpha,6Alpha)]- (9Ci) undergoes rigorous analytical testing to ensure identity, purity, and enantiomeric excess meet stringent specifications. Our quality assurance protocols are designed to support cGMP and ISO standards for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.