Description

(R)-2-((4-Nitrophenoxy)Methyl)Oxirane is a high-purity chiral epoxide building block of significant importance in asymmetric synthesis. Its enantiomerically pure structure makes it a critical intermediate for the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for creating complex, optically active molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of β-blockers, antiviral agents, and other enantiomerically pure drugs.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric catalysis.
• Fine Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing complex molecular architectures.
• Polymer Modification: Can be used to introduce chiral nitroaromatic functionalities into polymer backbones for specialty materials.

Basic Information

Product Name	(R)-2-((4-Nitrophenoxy)Methyl)Oxirane
CAS No.	125279-81-4
Molecular Formula	C9H9NO4
Molecular Weight	195.17 g/mol
Synonyms	(R)-(-)-Glycidyl 4-Nitrophenyl Ether; (R)-(-)-1-(4-Nitrophenoxy)-2,3-Epoxypropane; (R)-4-Nitrophenyl Glycidyl Ether; (2R)-2-[(4-Nitrophenoxy)methyl]oxirane; (R)-Epichlorohydrin 4-Nitrophenyl Ether; (R)-PNGE; (R)- enantiomer of Glycidyl 4-Nitrophenyl Ether
EINECS	Contact for details

Quality Control

Our (R)-2-((4-Nitrophenoxy)Methyl)Oxirane is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including chiral HPLC to confirm identity and purity. Certificates of Analysis (COA) detailing specific parameters such as assay, enantiomeric excess (ee), and impurity profiles are available upon request. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be stored away from direct light exposure. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.