Description

trans-2-Buten-2-Ylboronic Acid is a high-purity organoboron compound, specifically a vinylboronic acid derivative, widely recognized for its utility in advanced organic synthesis. Its primary value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex carbon-carbon bonds. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who are developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: A crucial building block for constructing complex drug candidates, particularly in creating carbon-carbon bonds for novel therapeutic agents.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides requiring specific molecular architectures.
• Materials Science Research: Serves as a monomer or precursor in the synthesis of organic electronic materials, such as polymers for OLEDs or conductive films.
• Suzuki-Miyaura Cross-Coupling Reactions: The primary application, acting as a versatile vinyl donor to introduce the 2-butenyl moiety into target molecules with high selectivity.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for transition metal catalysis.
• Academic and R&D Laboratories: A fundamental reagent for methodological development in synthetic organic chemistry and catalysis studies.

Basic Information

Product Name	trans-2-Buten-2-Ylboronic Acid
CAS No.	125261-72-5
Molecular Formula	C4H7BO2
Molecular Weight	97.91 g/mol
Synonyms	(E)-2-Buten-2-ylboronic Acid; trans-Crotylboronic Acid; (E)-Crotylboronic Acid; 2-Buten-2-ylboronic Acid (trans-); (E)-1-Methyl-1-propenylboronic Acid; B-(1-Methyl-1-propenyl)boronic Acid; trans-1-Methyl-1-propenylboronic Acid
EINECS	Contact for details

Quality Control

Our trans-2-Buten-2-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.