Description

2,3-o-(1-Methylethylidene)-L-Ribose is a protected sugar derivative, specifically an isopropylidene acetal of L-ribose. This compound is a crucial chiral building block and advanced pharmaceutical intermediate in organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for the development of nucleoside analogs, antiviral agents, and other bioactive molecules. Its defined stereochemistry and protective group make it invaluable for constructing complex molecular architectures with high precision.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of nucleoside-based antiviral and anticancer drugs.
• Nucleoside Chemistry: Used for the preparation of modified nucleosides and nucleotides for biochemical research and drug discovery.
• Carbohydrate Chemistry: Serves as a protected L-ribose derivative for the synthesis of complex oligosaccharides and glycoconjugates.
• Fine Chemical Synthesis: Employed as a building block for creating specialty chemicals, ligands, and catalysts requiring specific sugar scaffolds.
• Bioconjugation: Can be used to introduce sugar moieties into peptides, proteins, or other biomolecules.
• Academic & Industrial R&D: Essential for research in medicinal chemistry and chemical biology exploring sugar-derived compounds.

Basic Information

Product Name	2,3-o-(1-Methylethylidene)-L-Ribose
CAS No.	125165-31-3
Molecular Formula	C8H14O5
Molecular Weight	190.19 g/mol
Synonyms	1,2-O-Isopropylidene-α-L-ribofuranose; L-Ribose, 2,3-O-(1-methylethylidene)-; 2,3-O-Isopropylidene-L-ribofuranose; α-L-Ribofuranose, 1,2-O-(1-methylethylidene)-; Isopropylidene-L-ribose; L-(-)-1,2-O-Isopropylideneribofuranose; 2,3-O-(1-Methylethylidene)-α-L-ribofuranose
EINECS	Contact for details

Quality Control

Our 2,3-o-(1-Methylethylidene)-L-Ribose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.