Description

(E)-Methyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Acrylate CAS NO 125160-21-6 is a high-value, versatile boronic ester derivative featuring an acrylate moiety. This compound is a crucial building block in modern synthetic organic chemistry, enabling the efficient construction of complex molecules through cross-coupling reactions. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl and heterobiaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used to construct novel herbicide and fungicide candidates by introducing the acrylate-boronate functional group into target molecules.
• Material Science & Polymer Chemistry: Serves as a monomer or co-monomer for creating specialty polymers with tailored properties, such as self-healing materials or polymers with specific side-chain functionalities.
• Ligand & Catalyst Development: Employed in the synthesis of novel bidentate or tridentate ligands for transition metal catalysis.
• Chemical Biology & Probe Synthesis: Useful for labeling biomolecules or creating activity-based probes due to its reactive double bond and boronate handle.
• Organic Electronics: A building block for π-conjugated systems used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).

Basic Information

Product Name	(E)-Methyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Acrylate
CAS No.	125160-21-6
Molecular Formula	C₁₀H₁₇BO₄
Molecular Weight	212.05 g/mol
Synonyms	Methyl (2E)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)acrylate; Methyl trans-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propenoate; (E)-Methyl 3-(pinacolatoboryl)acrylate; Methyl 3-(pinacolatoboryl)acrylate, (E)-; trans-Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)acrylate; Pinacol (E)-3-(methoxycarbonyl)allylboronate; 125160-21-6
EINECS	Contact for details

Quality Control

Our (E)-Methyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Acrylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and isomeric integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Isomeric Purity (E/Z ratio)	≥95:5 (E:Z)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.