Description

1-(2,4-Difluoro-Phenyl)-1H-Pyrrole-2-Carbaldehyde is a high-purity fluorinated pyrrole derivative, a key advanced intermediate in modern organic synthesis. This compound matters for its role as a versatile building block in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation pesticides and herbicides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of organic electronic materials, such as components for OLEDs or conductive polymers, due to its electron-rich pyrrole core.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis, facilitating challenging chemical transformations.
• Fluorine Chemistry Studies: Acts as a model substrate for investigating the reactivity and effects of difluorophenyl groups in organic molecules.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	1-(2,4-Difluoro-Phenyl)-1H-Pyrrole-2-Carbaldehyde
CAS No.	125126-74-1
Molecular Formula	C11H7F2NO
Molecular Weight	207.18 g/mol
Synonyms	1-(2,4-Difluorophenyl)-1H-pyrrole-2-carboxaldehyde; 2,4-Difluoro-1-(2-formyl-1H-pyrrol-1-yl)benzene; 1H-Pyrrole-2-carboxaldehyde, 1-(2,4-difluorophenyl)-; 1-(2,4-Difluorophenyl)pyrrole-2-carbaldehyde; 2-Formyl-1-(2,4-difluorophenyl)pyrrole; 1-(2,4-Difluorophenyl)-2-formylpyrrole; 125126-74-1 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced intermediates. Every batch is characterized and controlled using modern analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We adhere to a quality management system and can support development projects requiring GMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.