Description

1-Dehydroxybaccatin Vi is a high-purity, advanced taxane intermediate derived from natural sources. This compound is of significant value in the pharmaceutical research and development sector, particularly for the semi-synthesis of complex anti-cancer agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of novel chemotherapeutic drugs and related bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the semi-synthetic pathway for potent anti-cancer drugs, including paclitaxel and docetaxel analogs.
• Biochemical Research: Used as a reference standard and building block in oncology research to study structure-activity relationships (SAR) of taxane derivatives.
• Fine Chemical Synthesis: Serves as a starting material for the chemical modification and development of new taxane-based compounds with potential therapeutic applications.
• Academic Research: Employed in university and institutional labs for pharmacological studies and the exploration of new synthetic methodologies.

Basic Information

Product Name	1-Dehydroxybaccatin Vi
CAS No.	125037-14-1
Molecular Formula	C29H36O10
Molecular Weight	544.59 g/mol
Synonyms	1-Dehydroxybaccatin VI; 10-Deacetylbaccatin V; 7-Epi-10-deacetylbaccatin V; NSC 311242; Taxane derivative 125037-14-1; 1-Desoxybaccatin VI; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-4,6,9,11,12a-pentahydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benz[1,2-b]oxet-2-yl acetate
EINECS	Contact for details

Quality Control

Our 1-Dehydroxybaccatin Vi is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). A Certificate of Analysis (COA) detailing batch-specific results is provided to ensure traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled temperature of 2-8°C to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.