Description

2-Propanone, 1-Chloro-1-Fluoro-1-Nitro- is a specialized halogenated nitro compound, a high-value intermediate in advanced organic synthesis. Its unique structure, featuring chlorine, fluorine, and nitro functional groups on a single carbon, makes it a versatile building block for introducing multiple reactive sites into target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors, where it is used to create novel active ingredients with specific properties. Global supply of this material is supported with consistent quality and technical data.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Organic Synthesis Building Block: Serves as a versatile precursor in complex organic reactions, including nucleophilic substitution and reduction, to create diverse chemical libraries.
• Material Science Research: Investigated for the synthesis of specialty polymers and advanced materials with unique electronic or surface properties.
• Fluorination Reagent Precursor: Can be utilized to develop or study new methodologies for introducing fluorine into organic molecules.

Basic Information

Product Name	2-Propanone, 1-Chloro-1-Fluoro-1-Nitro-
CAS No.	125013-74-3
Molecular Formula	C₃H₃ClFNO₂
Molecular Weight	139.51 g/mol
Synonyms	1-Chloro-1-fluoro-1-nitroacetone; 1-Chloro-1-fluoro-1-nitro-2-propanone; 1-Chloro-1-fluoro-1-nitropropan-2-one; Acetone, 1-chloro-1-fluoro-1-nitro-; Chlorofluoronitroacetone; CFN-acetone; α-Chloro-α-fluoro-α-nitroacetone
EINECS	Contact for details

Quality Control

Our 2-Propanone, 1-Chloro-1-Fluoro-1-Nitro- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with key parameters such as assay (by GC or HPLC), identity confirmation (by IR and/or NMR), and impurity profiles. Our quality systems are designed to meet the stringent requirements of GMP environments for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption or decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.